Resources to support your treatment journey

DAWNZERA works differently by using RNA technology to prevent HAE attacks.

To learn more at How DAWNZERA works

The most common side effects of DAWNZERA include injection site reactions, upper respiratory tract infection, urinary tract infection, and abdominal discomfort.

These are not the only possible side effects of DAWNZERA. Tell your doctor if you have any side effect that bothers you or that does not go away while using DAWNZERA.

Learn more about safety and side effects.  

Tell your doctor about any other medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

Store DAWNZERA in the refrigerator at 36 °F to 46 °F (2 °C to 8 °C) in the original carton.

If needed, DAWNZERA can be stored at room temperature up to 86 °F (30 °C) in the original carton for up to 6 weeks. If not used within 6 weeks stored at room temperature, throw away DAWNZERA.

Do not freeze.

Do not expose the autoinjector to heat.

Protect from direct light.

Ionis Every Step™ will check to see what information your doctor will need to send to support the insurance coverage process for you.

To help with this process, make sure your doctor has your up-to-date insurance information and knows how you're responding to your current treatment, including how many attacks you have been having, how intense they are, and how long they last. Your doctor will send this information with your prescription to Ionis Every Step. Reach out to your Patient Education Manager or Ionis Every Step with any other insurance questions you may have.

Ionis Every Step™ can help— a Case Manager can help you with potential financial assistance options for DAWNZERA. Call 1-844-444-4305,
Monday to Friday, 8 AM to 8 PM ET, for more information.

Ionis Every Step™ will work with your doctor's office to ask your insurance plan to reconsider their decision. This includes reviewing the denial
letter and collecting documentation from your doctor to submit for review. This is also known as the appeals process. If your doctor is unsure
about submitting an appeal, you can call their office to share why this treatment matters to you. Let them know you're interested in pursuing an
appeal and ask if they're able to help with the process.

Our team at Ionis Every Step™ will work with you and your doctor to understand your new insurance plan’s coverage. Reach out to your Patient Education Manager once you have your new insurance plan information. Ionis Every Step will use your new insurance plan information to check your coverage for DAWNZERA. Don’t worry—our team will work with your doctor to send any additional information to your new insurance plan and reach out with financial assistance options that you may be eligible for if DAWNZERA is not covered.

The Ionis Every Step™ Specialty Pharmacy will call to set up delivery of DAWNZERA right to your door. They will call from 1-844-444-4305. It 
may be helpful to save their phone number, so you know when they’re calling. DAWNZERA will not be shipped until you speak with the 
pharmacy about potential cost and to set up delivery.

You, your care partner, or doctor should inject DAWNZERA 1 time every 4 weeks or 1 time every 8 weeks depending on your prescribed dosing frequency.

To learn how to take DAWNZERA, you can watch the How to use DAWNZERA video for step-by-step instructions or review the Instructions for Use.

Hold the autoinjector against the skin for 10 seconds to make sure the full dose has been given. Remove the autoinjector by lifting it straight up.

To learn how to take DAWNZERA, you can watch the How to use DAWNZERA video for step-by-step instructions or review the Instructions for Use

If you miss a dose of DAWNZERA, administer the missed dose as soon as possible. Then inject DAWNZERA on the regular dosing schedule from the date of the most recently injected dose.

If your medication wasn't delivered when you were expecting it or it arrives damaged, reach out to your Patient Education Manager* for next steps.

*Patient Education Managers cannot give medical advice and do not replace your medical team. Contact your doctor for any medical concerns.

You can work with the Ionis Every Step™ Specialty Pharmacy to set up your next delivery.

Once you sign up for Ionis Every Step™, you will be paired with your dedicated Patient Education Manager.^† To sign up for Ionis Every Step and get connected with a Patient Education Manager, visit DAWNZERA.com/enroll or call 1-844-444-4305.

^†Patient Education Managers cannot give medical advice and do not replace your medical team. Contact your doctor for any medical concerns.

The Patient Education Manager^‡ is your primary Ionis Every Step partner who can connect you with other Ionis Every Step team members if you need more support:

• Case Manager: Can help you understand your insurance coverage and find potential ways to save on DAWNZERA^§
• Resource Navigator: Your guide for local social and emotional support.

^‡Patient Education Managers cannot give medical advice and do not replace your medical team. Contact your doctor for any medical concerns.

^§Subject to program terms, conditions, and limits. Ionis Every Step consent is required for participation in all Ionis Every Step affordability programs.

If you don’t have insurance, Ionis Every Step can help you understand what financial assistance options may be available to help you get DAWNZERA. Find out which affordability program may be right for you by calling 1-844-444-4305 Monday to Friday, 8 AM to 8 PM ET.

If you didn’t sign the form in your doctor’s office, you have other options to sign up for Ionis Every Step: 

• Complete online

• Call Ionis Every Step at 1-844-444-4305  Monday to Friday, 8 AM to 8 PM ET.