Ionis Every Step™: Get started and stay supported

Our dedicated team is focused on hereditary angioedema (HAE)—once you're prescribed DAWNZERA—they can help you understand how to get your medicine, how to use it, and provide resources to help you follow your doctor's treatment plan.

For more information, call Ionis Every Step at 1-844-444-4305, Monday to Friday, 8 AM to 8 PM ET

Let's take this step together

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Patient Education Manager​


You'll have someone by your side with Ionis Every Step—your Patient Education Manager* (PEM) will be your primary Ionis Every Step partner from the start and throughout your treatment journey once you are prescribed DAWNZERA and enroll in Ionis Every Step.

Your PEM can: 

  • Help you understand what happens next after your doctor prescribes DAWNZERA
  • Provide educational resources about DAWNZERA or HAE
  • Teach you how to use DAWNZERA

*Patient Education Managers cannot give medical advice and do not replace your medical team. Contact your doctor for any medical concerns.

Your dedicated Patient Education Manager will continue to reach out to provide support throughout your treatment journey

The Ionis Every Step team can guide you through:

Computer icon Navigating your insurance coverage

Ionis Every Step will work with your doctor and your insurance plan to help get DAWNZERA covered at the lowest possible cost and support timely access to the medicine.†

If you don’t have insurance, Ionis Every Step can help you understand what financial assistance options may be available to get DAWNZERA. Learn more here.

We know affordable medication is important to you. With Ionis Every Step, a commercially insured patient may pay as little as $0 out-of-pocket for each DAWNZERA prescription.†‡

†Insurance approval is not guaranteed. Ionis Every Step offers affordability programs for people prescribed DAWNZERA.

‡Eligibility restrictions: This program is not available to individuals who use any state or federal government-funded health care program to cover a portion of medication costs, such as Medicare, Medicaid, TRICARE, Department of Defense, or Veterans Administration, or any other state or federal government-funded health care program. Terms and conditions apply. Program subject to change or discontinue without notice, including in specific states.

Insurance card icon Receiving DAWNZERA

The Ionis Every Step Specialty Pharmacy will send DAWNZERA right to your front door. To avoid delays in receiving your medication, be sure to answer all calls from the Ionis Every Step Specialty Pharmacy at 1-844-444-4305. 

 

To learn about how to store DAWNZERA, click here.

Medical symbol icon Using DAWNZERA

Your dedicated Patient Education Manager can guide you through your treatment journey—one step at a time. Watch this video to learn how you’ll receive and administer your treatment. 

A preview of the how to use DAWNZERA™ video.
Icon of people having a conversation Continuing treatment

Ionis Every Step provides support to help you follow your doctor's treatment plan, including tracking and monitoring your treatment using DAWNZERA Direct, a digital companion. 

It allows you to 

  • Stay in touch with your PEM and Specialty pharmacy
  • View status updates
  • Schedule your next refill, use the swell diary, and access education information on DAWNZERA

Reach out to your Patient Education Manager to learn how to track your treatment journey with DAWNZERA Direct

Guide on getting started with DAWNZERA™. Guide on getting started with DAWNZERA™.

Getting Started with DAWNZERA

How you get DAWNZERA might be different than what you are used to. Use this guide to help you understand the steps to getting started with DAWNZERA.

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Taking the first step with Ionis Every Step is easy

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IMPORTANT SAFETY INFORMATION & INDICATION

Do not use DAWNZERA if you have had a serious allergic reaction, including anaphylaxis to donidalorsen or any of the ingredients in DAWNZERA.  

Before using DAWNZERA, tell your healthcare provider about all of your medical conditions, including if you: are pregnant or plan to become pregnant, are breastfeeding or plan to breastfeed. It is not known if DAWNZERA can harm your unborn baby, or if it passes into your breast milk and if it can harm your baby. 

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.  

What are the possible side effects of DAWNZERA?

DAWNZERA can cause serious side effects including allergic reactions. Allergic reactions can include rash, trouble breathing, chest pain, fainting, dizziness, feeling lightheaded, swelling of the face, lips or tongue, and itching. Stop using DAWNZERA and call your healthcare provider or get emergency help right away if you have any of these symptoms.

The most common side effects of DAWNZERA include injection site reactions (such as redness or pain at the injection site), upper respiratory tract infection, urinary tract infection, abdominal discomfort.

These are not all the possible side effects of DAWNZERA. Tell your healthcare provider or treatment team about any side effects you may have. 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call 1-800-FDA-1088.  

INDICATION

DAWNZERA™ (donidalorsen) is a prescription medicine used to prevent hereditary angioedema (HAE) attacks in adults and children 12  years of age and older. 

It is not known if DAWNZERA is safe and effective in children under 12 years of age. 

Please see full Prescribing Information and Patient Information for DAWNZERA.