Starting Treatment
Starting Treatment Ionis Every Step™ Support
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Getting started with Ionis Every Step™

Ionis Every Step provides support every step of the way as a patient support program. DAWNZERA will be sent from the Ionis Every Step Specialty Pharmacy right to your front door.

See below for an overview of the steps to getting DAWNZERA and how Ionis Every Step provides personal support.

Starting Treatment

Steps to getting started

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Step 1

Getting started with Ionis Every Step

Once you're prescribed DAWNZERA, you have a few options to sign up for Ionis Every Step:

After signing up, you will get a Welcome Kit and a call from your dedicated Patient Education Manager* to welcome you into the program, answer any questions you may have, and schedule your injection training.

*Patient Education Managers cannot give medical advice and do not replace your medical team. Contact your doctor for any medical concerns.

Get to know your autoinjector by using the practice pen in your Welcome Kit.

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Step 2

Navigating your insurance coverage

Ionis Every Step works with you and your doctor to help get insurance approval for DAWNZERA and will provide updates along the way.
Your doctor's office may need to send information to your insurance plan to get approval for DAWNZERA.

To help with this process, make sure that your doctor's office has up-to-date details about:

  • How many attacks you have each month, how intense they are, and how long they last

  • Any medications that you're taking or have taken in the past

Want to track your treatment journey with DAWNZERA? Reach out to your Patient Education Manager to signup for DAWNZERA Direct, your digital companion for tracking your DAWNZERA treatment journey.

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Step 3

Receive DAWNZERA

Ionis Every Step Specialty Pharmacy will reach out to set up delivery. It is important to answer your phone to avoid delays in receiving your medication. When you receive DAWNZERA, keep it in the refrigerator between 36°F to 46°F (2°C to 8°C) in the original carton. DAWNZERA can be stored at room temperature up to 86°F (30°C) in the original carton for up to 6 weeks. If not used within the 6 weeks stored at room temperature, throw out DAWNZERA.

Save 1-844-444-4305 in your phone and know when the pharmacy is calling.

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Step 4

Use DAWNZERA

Talk to your dedicated Patient Education Manager or doctor about any remaining questions you have on using DAWNZERA after your injection training.

A preview of the how to use DAWNZERA video.

Need a reminder?

DAWNZERA is delivered through a convenient, single-use autoinjector, and a few quick steps can help you feel confident you’re doing it right. Watch this video to learn how you’ll receive and administer your treatment.

Connect with your Patient Education Manager when you have finished your injection so they can continue to support you along your treatment journey.

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Step 5

Continued treatment

Ionis Every Step provides support to help you follow your doctor's treatment plan

  • Your dedicated Patient Education Manager will continue to reach out to provide support throughout your treatment journey

  • Continue to track and monitor your treatment using DAWNZERA Direct

Ionis Every Step Support

Support to help you take your first and next steps

Ionis Every Step is here for you from your first step to every next step. Our dedicated team is focused on HAE—they can help you understand how to get your medicine, how to use it, and provide resources to help you follow your doctor's treatment plan.

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Meet your dedicated Patient Education Manager†

Ionis Every Step connects you with a dedicated Patient Education Manager† right from the start to help guide you through your treatment journey—one step at a time.

  • Help you understand what happens next after your doctor prescribes DAWNZERA, including an overview of the insurance process

  • Answer your questions and provide educational resources about DAWNZERA or HAE

  • Teach you how to use DAWNZERA- in person, or virtually

  • Connect you to additional Ionis Every Step members if you need more support

  • Reach out to provide support throughout your treatment journey

†

Patient Education Managers cannot give medical advice and do not replace your medical team. Contact your doctor for any medical concerns.

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Insurance navigation‡

When it comes to insurance, Ionis Every Step will work with your doctor and your insurance plan to:

  • Help get DAWNZERA covered at the lowest possible cost and support timely access to the medicine, regardless of your financial situation

  • Provide updates at every step

If you don't have insurance, Ionis Every Step can help you understand what financial assistance options may be available to get DAWNZERA.

‡

Insurance approval is not guaranteed. Ionis Every Step offers affordability programs for people prescribed DAWNZERA.

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Affordability programs

Ionis Every Step is committed to helping you access your Ionis medication. There are many financial assistance options available regardless of your insurance.

Quick Start§

  • Ionis Every Step gets you started on therapy quickly with a quick-start shipment at no cost if insurance coverage is delayed

Copay assistance

  • Ionis Every Step is here to help you save on DAWNZERA. If you have commercial (private) insurance, you may pay as little as $0 out-of-pocket for each prescription

  • Find out which affordability program may be right for you by calling 1-844-444-4305, Monday to Friday, 8 AM to 8 PM ET

§

Terms and conditions apply. Program subject to change or discontinue without notice, including in specific states.

Eligibility restrictions: This program is not available to individuals who use any state or federal government–funded healthcare program to cover a portion of medication costs, such as Medicare, Medicaid, TRICARE, Department of Defense, or Veterans Administration, or any other state or federal government–funded healthcare program. Terms and conditions apply. Program subject to change or discontinue without notice, including in specific states.

Track your treatment journey with DAWNZERA Direct

DAWNZERA Direct is your digital companion for managing your DAWNZERA treatment journey. With DAWNZERA Direct, you have helpful resources at your fingertips every step of the way.

Stay in touch

  • Schedule a call with your Patient Education Manager and easily connect with the Ionis Every Step Specialty Pharmacy

Keep track

  • Allows you to track and monitor your treatment journey

  • Refill reminders for the next dose

Learn more

  • Educational information on HAE and DAWNZERA, such as an injection training video and other helpful resources

  • Receive updates via push notifications, email, or SMS, based on your preference

Reach out to your Patient Education Manager to sign up for DAWNZERA Direct and begin tracking your treatment journey today.

Taking the first step with Ionis Every Step is easy, Call 1-844-444-4305, Monday to Friday, 8 AM to
8 PM ET, to get started today!

IMPORTANT SAFETY INFORMATION & INDICATION

Do not use DAWNZERA if you have had a serious allergic reaction, including anaphylaxis to donidalorsen or any of the ingredients in DAWNZERA.

Before using DAWNZERA, tell your healthcare provider about all of your medical conditions, including if you: are pregnant or plan to become pregnant, are breastfeeding or plan to breastfeed. It is not known if DAWNZERA can harm your unborn baby, or if it passes into your breast milk and if it can harm your baby.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of DAWNZERA? 
DAWNZERA can cause serious side effects including allergic reactions. Allergic reactions can include rash, trouble breathing, chest pain, fainting, dizziness, feeling lightheaded, swelling of the face, lips or tongue, and itching.  Stop using DAWNZERA and call your healthcare provider or get emergency help right away if you have any of these symptoms.

The most common side effects of DAWNZERA include injection site reactions (such as redness or pain at the injection site), upper respiratory tract infection, urinary tract infection, abdominal discomfort.

These are not all the possible side effects of DAWNZERA. Tell your healthcare provider or treatment team about any side effects you may have.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call 1-800-FDA-1088.  

INDICATION DAWNZERA™ (donidalorsen)  is a prescription medicine used to prevent hereditary angioedema (HAE) attacks in adults and children 12  years of age and older.

It is not known if DAWNZERA is safe and effective in children under 12 years of age. 

Please see full Prescribing Information and Patient Information for DAWNZERA.